Mike DeCarlo  is an American comics artist. He is best known for his work for DC Comics in the 1980s inking the artwork of such artists as George Pérez, Greg LaRocque, Keith Giffen, and Jim Aparo.

DeCarlo has worked on various titles including Atari Force, Cartoon Network Block Party, Crisis on Infinite Earths, Fantastic Four, and Simpsons Comics as well as adaptations of the Warner Bros. stable of cartoons including Looney Tunes, Animaniacs, Pinky and the Brain and Superman & Bugs Bunny.